Topical Cosmetic Exosome Biologics for Medspas & Aesthetic Clinics

Medspas · Aesthetic Clinics · Dermatology · Licensed Professionals Only

MEDxTeam supplies topical cosmetic exosome biologics wholesale to licensed medspas, aesthetic practices, and dermatology clinics. Credential verification is required prior to purchase. These products are supplied for topical cosmetic professional use only.

Grow your practice... & Please your Patients!

Important: These products are not FDA-approved drugs or therapeutic agents and are not intended to diagnose, treat, cure, or prevent any disease or condition. For topical cosmetic use only. Not for injection or therapeutic use. All professional application decisions are at the sole discretion of the licensed practitioner.

3DExo+™ Matrix — 60 Billion EVs · 1mL · Topical Cosmetic Biologic

Topical cosmetic exosome biologic derived from 3D bioreactor-cultured Wharton's Jelly UCT-MSCs. 60 billion NTA-verified extracellular vesicles per vial. For use in post-procedure cosmetic recovery and aesthetic topical protocols.

60 Billion EVs — NTA-verified particle count, lot-documented
3D bioreactor-cultured — up to 19.4x higher EV yield vs. 2D flat culture
Liquid cryopreserved — not lyophilized
Xeno-Free · Serum-Free · Endotoxin-tested · Lot-specific CoA
Manufactured in an FDA-registered, AATB-Accredited, cGMP-aligned US facility

Cosmetic application context (at practitioner discretion): Post-microneedling topical application · Post-RF microneedling cosmetic support · Post-laser resurfacing cosmetic recovery · Post-chemical peel topical support · Stand-alone topical cosmetic facial protocols

For topical cosmetic use only · Not for injection · Not FDA-approved · Licensed professionals only

Dermal Papillary Secretome Matrix+ — 150 Billion EVs · 1.8mL · Topical Cosmetic Biologic

Ultra-potent topical cosmetic exosome biologic with more than twice the EV load of standard 60B serums. 1.8mL volume for broader coverage cosmetic protocols. For topical cosmetic professional use only.

150 Billion EVs — NTA-verified, more than 2x the EV load of 60B format
1.8mL volume — suitable for full-area cosmetic protocols
3D bioreactor-cultured — Wharton's Jelly UCT-MSC origin
Liquid cryopreserved · Xeno-Free · Serum-Free · Lot-specific CoA
Manufactured in an FDA-registered, AATB-Accredited, cGMP-aligned US facility

For topical cosmetic use only · Not for injection · Not FDA-approved · Licensed professionals only

Built for Practices Leading Regenerative Medicine

Clinical-grade biologics formulated for the specific demands of your practice.

MedSpa

pain_ortho

hair_restoration

Medspas

Add premium exosome facials, microneedling enhancement, and skin rejuvenation protocols to your service menu. High margin, high demand, fully compliant.

Orthopedic & Pain Clinics

NTA-verified 60B exosome vials with documented particle counts, sterility testing, and lot-specific COAs — engineered for the precision demands of orthopedic and regenerative pain protocols. Stem Cells also.

Hair Restoration Centers

Differentiate from PRP-only competitors with 3D-cultured exosome biologics offering superior particle concentration, consistency, and scalp regenerative signaling potential.

Spinal Surgery & Interventional Pain Practices

Regenerative Biologics for Spinal Surgery & Interventional Pain Practices

Spinal Surgery · Interventional Pain · Neurosurgery · Spine Rehab
[Protocols Available]

Wellness & Longevity

Veterinary - Large / Small Animals

Veterinary professionals use exosomes, particularly derived from mesenchymal stem cells (MSCs), as innovative cell-free therapies to treat inflammation, osteoarthritis, and wounds in dogs, cats, and horses.
Search any AI for "Exosomes used by Veterinary professionals"

How to Enroll Your Clinic?

Submit Your Enrollment

Complete our quick clinic enrollment form. Takes less than 5 minutes. Proof of licensure required.

Enroll Here

Get Approved & Access Pricing

Most clinics are approved within 1 business day. Unlock wholesale pricing, COAs, and NTA data immediately.

View Standards

Place Your Order & Get Started

Orders ship overnight on dry ice. Most clinics receive their first order within 2–3 business days of approval.

View Products

Why MEDxTeam?

Every product we ship is engineered to the same standard we'd demand ourselves.

98% Post-Thaw Viability

No animal-derived components. Reduced biologic risk, improved consistency.

3D Culture · 20x Potency

Bioreactor-grown with up to 19.4x higher yield vs. standard 2D methods.

98% Post-Thaw Viability

Validated cryopreservation preserves cellular integrity and consistent dosing.

Ethically Sourced UCT-MSCs

AATB-accredited. FDA Type II Master File. 3-generation donor screening.

Wharton's Jelly UCT-MSCs

Biologically younger, highly proliferative, and naturally immune-privileged.

Live Cryopreserved · Never Lyophilized

Native membranes preserved. No freeze-drying that degrades bioactivity.

Multipotent UCT-MSCs

Differentiates into bone, cartilage, muscle, and connective tissue lineages.

Third-Party Tested · Full Traceability

NTA-verified particle count and lot-specific COAs on every batch.

Are our biologics FDA‑approved?

No. Our 3D UCT‑MSC and exosome products are manufactured in FDA‑registered, ISO‑compliant facilities under cosmetic good‑manufacturing practices, but they are not FDA‑approved drugs or biologics. The U.S. Food and Drug Administration states that exosome products intended to treat diseases or conditions in humans require FDA approval and “there are currently no FDA‑approved exosome products.” We strictly market our products for research or topical cosmetic use and do not make medical claims.

What makes 3D‑cultured MSCs better than traditional 2D?

Three‑dimensional culture mimics the body’s natural environment and dramatically increases exosome production and potency. In a hollow‑fiber 3D bioreactor, MSCs produced up to 19.4‑fold more exosomes than in a standard 2D flask, and the supernatants were 15.5‑fold more concentrated. 3D culture also allows continuous harvesting of exosomes, requires far fewer plastic flasks and less labour, and can produce an equivalent yield in less than 30 minutes per day. These 3D‑derived exosomes show superior uptake by target cells and stronger effects .compared with 2D exosomes.
These 3D-derived exosomes demonstrate superior biological signaling profiles and cellular uptake characteristics compared with 2D exosomes, supporting the enhanced potency behind our 3DExo+™ platform

Can I inject these biologics?

Our biologics are manufactured to pharmaceutical-grade quality standards, including sterility, endotoxin, and viability testing. They are labeled for topical and research use only. Any clinical application is at the sole discretion and professional responsibility of the licensed practitioner, in accordance with all applicable federal and state regulations.

Who are our products intended for?

Our biologics are supplied exclusively to licensed medical professionals. How products are used within a practitioner's clinical protocols is at their sole discretion and in accordance with applicable federal and state regulations. We do not advise on indications, applications, or patient protocols.

What does “xeno‑free ”mean?

“Xeno‑free” means that all components are derived from the same species (human) or are recombinant, so no animal‑derived ingredients such as fetal bovine serum are present. RegMedNet explains that xeno‑free media contain only proteins of human origin or recombinant quality. Using xeno‑free, serum‑free manufacturing reduces the risk of introducing foreign proteins or pathogens, making the product safer and more consistent for cosmetic or research use.

MSC Exosomes
The Future of Regenerative & Functional Medicine

See our Products & Pricing <CLICK>
USE: Used by many doctors in... cosmetic and aesthetic medicine, orthopedics, and dermatology, hair restoration, and tissue repair. They are also being investigated for potential applications in cardiovascular, neurological, and organ-related diseases. (Note)
NOTE: We sell several variants of Exosomes & Stem Cells. Each has their own regulatory standards to be considered.
MSC Exosomes are becoming known as the cutting edge of regenerative medicine. Exosomes that are SAFE, PURE, and POTENT show zero side effects; can pass through the blood brain barrier; and are used by pro-athletes, ascetics, orthopedics, disease treatment, etc. (source)
Lipid Nanoparticles (LNPs) are not technically exosomes, although they are often described as synthetic, functional mimics of them. Exosomes are natural, cell-derived vesicles, while LNPs are artificially engineered carriers. Exosomes are often called "nature's lipid nanoparticles" because they perform similar functions, like delivering mRNA. (source)
Stem Cells vs Exosomes: (source)
- Stem cell-derived exosomes are generally less immunogenic than cells (i.e. Stem Cells). Thus, “off the shelf” products may readily be developed using exosomes with negligible immunogenicity.
- Stem cells require special care and processing, which is much less rigorous for exosomes because they are not cells. Exosomes can be frozen and stored without cryo- preservatives with no loss in their biochemical activities. They can also be lyophilized.
- Stem cells have the potential to transform into other cells, including oncogenic cells. Exosomes lack this capacity (safer), but may be modified in various ways to affect cargo and delivery.
- MSC Exosomes are much safer and more effective than Stem Cells. *Harvard Library: Exosomes and Their Therapeutic
  Potentials of Stem Cells (CLICK)
- Stem Cells have important applications where they are the preferred tool. ex. Spinal & Intrathecal Biologic Protocol - they can undergo endoneural differentiation inside the cerebrospinal fluid (CSF) environment.
- We have both 351(a) and 361 labeled Exosomes.
SERVICES: We offer comprehensive exosome training, protocols, onboarding, and consulting to ensure clinicians bring Exosomes to their practice smoothly and effectively. From understanding proper handling to integrating the therapy into care pathways, our training support turns innovation into everyday clinical impact.
Not all exosomes are created equal. Are they consistently compliant including being SAFE, PURE, and POTENT?

Common Product Terms:
- ✅ Extracellular Vesicles (EVs)
  ✅ MSC-Derived Extracellular Vesicles
  ✅ Biologic Nanoparticles
  ✅ Regenerative Nanoparticles
  ✅ Signal-Cell Derived Vesicles
  ✅ Stem Cell-Derived Signaling Vesicles
  ✅ MSC-Derived Secretome
  ✅ The most advanced regenerative medicine
- Exosomes are amazing.
- Let's talk!